Abstract Library

#2706 A New Possibility in SI-NET Surgery by Using a New β- Probe and 90Y-DOTATOC: A Pilot Study

Introduction: In neuroendocrine tumor (NET), complete surgery could better the prognosis of this disease: radioguided surgery (RGS) with beta-radioisotopes, as 90Y, is a novel approach focused on developing a new probe which, detecting electrons and operating with low background, provides a clearer delineation of the margins of lesions with low radiation exposition for surgeons.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Grana C

Authors: Grana C, Bertani E, Collamati F, Faccini R, Pisa E,

Keywords: Small intestine neuroendocrine tumors, liver metastases, β- probe, 90Y-DOTATOC,

#2288 Predicting Resectability of Primary Tumor and Mesenteric Lumps in Patients with Small Intestine Neuroendocrine Tumors

Introduction: Vascular infiltration and mesenteric fibrosis may jeopardize resection of primary tumor (PT) and mesenteric metastatic lumps (MLs) in small-intestine neuroendocrine tumors (SI-NETs).

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Piccioli A, Funicelli L, Fazio N, Borin S, Petz W,

Keywords: small intestine neuroendocrine tumors, mesenteric fibrosis, mesenteric vascular infiltration, resection of primary tumor, mesenteric metastatic lumps, radical surgery,

#1461 Whole Exome Sequencing of Three Families with Small Intestine Neuroendocrine Tumors

Introduction: Small intestine neuroendocrine tumors (siNETs) are the most prevalent small intestine neoplasms. However, familial siNETs are rarely described.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: Beyens M, Vandamme T, Goepfert A, Van Camp G, Hofland L,

Keywords: Familial siNET, whole exome, candidate gene,

#1202 Role of Amplifications in the PIK3/Akt/mTOR-Pathway in Neuroendocrine Tumors of the Small Intestine

Introduction: Amplifications in the PIK3/Akt/mTOR pathway can lead to increased proliferation and reduced apoptosis, resulting in the development of various cancers. Recently, amplifications of Akt1/2, PDGFRα/β and mTOR in small intestine neuroendocrine tumors (siNET) have been shown.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author:

Authors: Hoffmeister M, Sperveslage J, Anlauf M, Petersen K, Gress T,

Keywords: NET, gene amplification, mTOR pathway,

#1186 Significance of ATRX/DAXX Expression and Alternative Lengthening of Telomeres in Insulinomas and Neuroendocrine Tumors of Small Intestine.

Introduction: ATRX and DAXX mutations associated with alternative lengthening of telomeres ( ALT) phenotype have been shown as one of the major altered pathways in pancreatic neuroendocrine tumors (PanNET).

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author:

Authors: Neumayer B, Normand L, Hoffmeister M, Friemel J, Perren A,

Keywords: DAXX, ATRX, Alternative lengthening of telomeres, neuroendocrine tumor, Insulinoma,